2015-present, Senior engineer, Shanghai Institute of Immunity and Infection, CAS
2009-2015, Associate professor, Shanghai Institutes for Biological Sciences, CAS

2006-2009, Postdoctoral fellow, Carolinas Medical Center, USA

2001-2006, Ph.D., Shanghai Institute of Biochemistry and Cell Biology, CAS

1998-2001, M.S., Henan Normal University (HNNU)
1994-1998, B.S., Henan Normal University (HNNU)

Our lab focuses on pathogen discovery, detection and isolation. We use molecular, cellular and virological research methods in P2 level biosafety laboratory to isolate and identify pathogens of emerging and emergent infectious diseases, as well as antiviral drug screening and mechanism research, and to conduct respiratory/intestinal and other common virus diagonstic methods and epidemiological analysis.

Selected publications  (^#Co-first author;*Co-corresponding author）

1.      Yang J^#, Yue L^#, Shen B, Yang Z, Shao J, Miao Y, Ouyang R*, Hu Y*. Exploring the Inhibitory Effect of AgBiS₂ Nanoparticles on Influenza Viruses. Int J Mol Sci. 2023 Jun 16;24(12):10223.

2.      Yang Z, Yang J, Yue L, Shen B, Wang J, Miao Y*, Ouyang R*, Hu Y*. Enhancement Effects and Mechanism Studies of Two Bismuth-Based Materials Assisted by DMSO and Glycerol in GC-Rich PCR. Molecules. 2023 Jun 2;28(11):4515.

3.      Li H^#, Dong W^#, Wang J^#, Yu D, Qian D, Yue L, Jiu Y, Hu Y*. The global epidemic trend analysis of influenza type B drug resistance sites from 2006 to 2018. J Infect Dev Ctries. 2023 Jun 30;17(6):868-873.

4.      Yang Z, Shen B, Yue L, Miao Y*, Hu Y*, Ouyang R*. Application of Nanomaterials to Enhance Polymerase Chain Reaction. Molecules. 2022 Dec 13;27(24):8854.

5.      Yang J, Yue L, Yang Z, Miao Y, Ouyang R*, Hu Y*. Metal-Based Nanomaterials: Work as Drugs and Carriers against Viral Infections. Nanomaterials (Basel). 2021 Aug 20;11(8):2129.

6.      Zuo L, Peng, K, Hu Y*, Xu, Q*. Genotypic Methods for HIV Drug Resistance Monitoring: The Opportunities and Challenges Faced by China. Current HIV Research, 2019, 17(4): 225-239.

7.      Li Y^#, Wan Z^#, Hu Y^#, Zhou Y, Chen Q, Zhang C. A mismatch-tolerant RT-quantitative PCR: application to broad-spectrum detection of respiratory syncytial virus. Biotechniques. 2019 May;66(5):225-230.

8.      Hu Y*, Wan Z, Mu Y, Zhou Y, Liu J, Lan K, Zhang C*. A quite sensitive fluorescent loop-mediated isothermal amplification for rapid detection of respiratory syncytial virus. J Infect Dev Ctries. 2019 Dec;13(12):1135-1141.

9.      Hu Y, Wan Z, Zhou YH, Smith D, Zheng YT, Zhang C*. Identification of two new HIV-1 circulating recombinant forms (CRF87_cpx and CRF88_BC) from reported unique recombinant forms in Asia. AIDS Res Hum Retroviruses. 2017 Apr;33(4):353-358.

10.   Wan Z^#, Zhang Y^#, He Z, Liu J, Lan K, Hu Y*, Zhang C*. A melting curve-based multiplex RT-qPCR assay for simultaneous detection of four human coronaviruses. Int J Mol Sci. 2016, 17(11). pii: E1880.

11.   Liu T, Wan Z, Liu J, Zhang L, Zhou Y, Lan K, Hu Y*, Zhang C*. A Novel Real-time Reverse Transcription-Polymerase Chain Reaction Assay with Partially Double-Stranded Linear DNA Probe for Sensitive Detection of Hepatitis C Viral RNA. J Virol Methods. 2016; 236:132-138.