2017-present, Associated professor, Shanghai Institute of Immunity and Infection, CAS
2013-2017, Research assistant, Institut Pasteur of Shanghai, CAS 
2008-2013, Ph.D., Fudan University, China
2004-2008, Bachelor’s Degree, Central South University, China

I mainly work on two fungal species, Candida spp. (e.g., Candida albicans) and Cryptococcus spp. (e.g., Cryptococcus gattii). My reach focuses on the host-fungal interaction and the development of novel anti-fungals and vaccines.

Selected publications

1.     Wang Y^#, Mao Y^#, Chen X, Huang X, Jiang Z, Yang K, Tian X, Jiang T, Zou Y, Ma X, Xu C, Zhou Z, Wu X, Pan L, Liang H^*, Zhong L^*, Chen C^*. Homeostatic control of an iron repressor in a GI tract resident. Elife. 2023 May 25;12: e86075.

2.     Wang Y^#, Zou Y^#, Chen X, Yin Z, Zhang B, Xu Y, Zhang Y, Huang X, Yang W, Xu C, Jiang T, Zhou Z, Ji Y, Liu Y, Hu L, Zhou J, Liu N, Huang G, Chen C^*, Zhou D^*. Innate immune responses against the fungal pathogen Candida auris. Nat Commun. 2022 Jun 21;13(1):3553.

3.     Wang Y, Zhou J, Zou Y, Chen X, Liu L, Qi W, Huang X, Chen C^*, Liu N^*. Fungal commensalism modulated by a dual action phosphate transceptor. Cell Rep. 2022 Jan 25;38(4):110293.

4.     Chen C^*. and Huang X. Candida albicans Commensalism and Human Diseases. In book: Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases. E.d. Jun Sun and Dudeja PK. Physiology in Health and Disease. Springer. 2018, ISBN 978-1-4939-7533

5.     Huang X^#, Chen X^#, He Y^#, Yu X, Li S, Gao N, Niu L, Mao Y, Wang Y, Wu X, Wu W, Wu J, Zhou D, Zhan X, Chen C^*. Mitochondrial complex I bridges a connection between regulation of carbon flexibility and gastrointestinal commensalism in the human fungal pathogen Candida albicans. PLOS Pathogens, 2017 Jun1,13(6): e1006414.

6.     Huang X, Wang H, Meng L, Wang Q, Yu J, Gao Q, Wang D^*. Role of eosinophils and apoptosis in PDIMs/PGLs deficient mycobacterium elimination in adult zebrafish. Dev Comp Immunol, 2016 Jun,59: 199-206.

7.     Tian Y^#, Gao N^#, Ni Q, Mao Y, Dong D, Huang X, Jiang C, Li Z, Zhang L, Wang X, Peng Y^* and Chen C^*. Sequence modification of the master regulator Pdr1 interferes with its transcriptional autoregulation and confers altered azole resistance in Candida glabrata. FEMS Yeast Research, 2018 Jun1,18(4).

8.     Yu J, Tran V, Li M, Huang X, Niu C, Wang D, Zhu J, Wang J, Gao Q^*, Liu J^*. Both phthiocerol dimycocerosates and phenolic glycolipids are required for virulence of Mycobacterium marinum. Infect Immun.2012,80(4):1381-9