Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

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2025-06

SCI IMMUNOL | Researchers Discover Radiotherapy Enhances Anticancer CD8 T Cell Responses by cGAMP Transfer through LRRC8A/C Volume-Regulated Anion Channels

Radiotherapy and chemotherapy are widely practiced clinical applications with the ability to shape the tumor immune microenvironment, in which the cGAS-cGAMP-STING pathway plays a crucial role in augmenting anticancer immunity.Studies have suggested that transferring cGAMP from tumor cells to inf...

26

2025-05

Nature Communications | Researchers Identify a New Strategy to Overcome Drug Resistance in the Deadly Fungus Candida auris

On May 20, 2025, a research team led by Prof. CHEN Changbin at the Shanghai Institute of Immunity and Infection of the Chinese Academy of Sciences, published a study titled “Targeting epigenetic regulators to overcome drug resistance in the emerging human fungal pathogen Candida auris” in Natur...

26

2025-05

Nucleic Acids Research | First Open-Access mRNA Design Platform mRNAdesigner Enhances Nucleic Acid Drug Development Efficiency

In a study published in Nucleic Acids Research on May 19, entitled “mRNAdesigner: an integrated web server for optimizing mRNA design and protein translation in eukaryotes,” Professor HAO Pei from the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences, introd...

02

2025-02

NAT IMMUNOL | Researchers Discover Anti-Cancer Potential of Immune Modulator's Short Form

In a study published in Nature Immunology on January 31, Prof. MENG Guangxun from the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences, and Prof. LIU Chen-Ying from Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, unveiled a novel mechanism ...