Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

02

2018-04

Institut Pasteur of Shanghai reveals that recombinant ZIKV envelope protein elicited protective immunity against ZIKV in immunocompetent mice

On March 28th, 2018, Plos One published a research work entitled “Recombinant Zika virus envelope protein elicited protective immunity against Zika virus in immunocompetent mice” from Xia Jin’s unit, Institute Pasteur of Shanghai, Chinese Academy of Science.
　　Zika virus (ZIKV) is an em...

29

2018-03

Researchers of Institut Pasteur of Shanghai revealed the function and mechanism of MLL5, an epigenetic regulator, in regulating antiviral immune response

On March 28th, 2018, Nature Communications published a research work entitled “MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation" from Yan Zhang’s unit, Institute Pasteur of Shanghai, Chinese Academy of Sciences. This work demonstrates that MLL5, ...

02

2018-03

Researchers of Institut Pasteur of Shanghai unveal the Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP

Endoplasmic reticulum (ER) stress response is mediated by dissociating with binding immunoglobulin protein (Bip) and controls cell fate. ER stress leads to the gene expression such as ATF4 and C/EBP homologous protein (CHOP).
　　B cell receptor (BCR) signaling is a physiologic ER stress trigger,...

01

2018-03

Institut Pasteur of Shanghai reveals that the chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis

On February 26, Journal of Hematology & Oncology published the collaborative research work entitled "The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis" from Yan Zhang’s unit, Institute Pasteur of Shanghai, Chinese Academy of Sciences and Bin Zhou...