Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

20

2015-05

SHP-2 regulates C-type lectin receptor–induced activation of the kinase Syk and anti-fungal TH17 responses

Fungal infections are regarded as a serious health threat worldwide because they cause severe mucosal and systemic candidiasis in elderly people and patients with AIDS, organ transplantation or immunodeficiency. C-type lectin receptors (CLRs) dectin-1, dectin-2/3 and Mincle play a pivotal role in...Fungal infections are regarded as a serious health threat worldwide because they cause severe mucosal and systemic candidiasis in elderly people and patients with AIDS, organ transplantation or immunodeficiency. C-type lectin receptors (CLRs) dectin-1, dectin-2/3 and Mincle play a pivotal role in...

23

2014-12

Researchers at Institut Pasteur of Shanghai developed a mammalian-cell adapted influenza A virus vaccine doner strain

Recently, Vaccine published a research work entitled “A Vero-cell-adapted vaccine donor strain for influenza A virus with an accelerated viral transport resulted from serial passages” from the unit of molecular virology, Institut Pasteur of Shanghai, Chinese Academy of Sciences. Recently, Vaccine published a research work entitled “A Vero-cell-adapted vaccine donor strain for influenza A virus with an accelerated viral transport resulted from serial passages” from the unit of molecular virology, Institut Pasteur of Shanghai, Chinese Academy of Sciences.
　　Influenza v...

16

2014-12

Researchers at Institut Pasteur of Shanghai discover the key pattern recognition receptor for Hepatitis C Virus (HCV)

On November 21, Journal of Hepatology published an article online entitled “MDA5 Plays a Critical Role in Interferon Response during Hepatitis C Virus Infection” from the Unit of Viral Hepatitis, Institut Pasteur of Shanghai, Chinese Academy of Sciences. On November 21, Journal of Hepatology published an article online entitled “MDA5 Plays a Critical Role in Interferon Response during Hepatitis C Virus Infection” from the Unit of Viral Hepatitis, Institut Pasteur of Shanghai, Chinese Academy of Sciences.
　　Hepatitis C virus (HCV) is an import...

04

2014-12

Researchers at Institut Pasteur of Shanghai discover a novel mechanism whereby Hepatitis B Virus promotes liver injury

On November 26, the international academic journal, Journal of Virology, published an article online entitled “Hepatitis B core protein sensitizes hepatocytes to tumor necrosis factor-induced apoptosis by suppression of the phosphorylation of mitogen-activated protein kinase kinase 7”. This res...On November 26, the international academic journal, Journal of Virology, published an article online entitled “Hepatitis B core protein sensitizes hepatocytes to tumor necrosis factor-induced apoptosis by suppression of the phosphorylation of mitogen-activated protein kinase kinase 7”. This res...