Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

04

2014-12

Researchers at Institut Pasteur of Shanghai discover a novel mechanism whereby Hepatitis B Virus promotes liver injury

On November 26, the international academic journal, Journal of Virology, published an article online entitled “Hepatitis B core protein sensitizes hepatocytes to tumor necrosis factor-induced apoptosis by suppression of the phosphorylation of mitogen-activated protein kinase kinase 7”. This res...On November 26, the international academic journal, Journal of Virology, published an article online entitled “Hepatitis B core protein sensitizes hepatocytes to tumor necrosis factor-induced apoptosis by suppression of the phosphorylation of mitogen-activated protein kinase kinase 7”. This res...

21

2014-10

Researchers at Institut Pasteur of Shanghai discover a novel mechanism that KSHV impairs host innate immunity

On October 15, 2014, the International academic Journal of Virology published an article online entitled “Kaposi's Sarcoma-Associated Herpesvirus-Encoded RTA Impairs Innate Immunity via Ubiquitin-mediated Degradation of MyD88” by Prof. Ke Lan’s Lab at Institut Pasteur of Shanghai, Chinese Acad...On October 15, 2014, the International academic Journal of Virology published an article online entitled “Kaposi's Sarcoma-Associated Herpesvirus-Encoded RTA Impairs Innate Immunity via Ubiquitin-mediated Degradation of MyD88” by Prof. Ke Lan’s Lab at Institut Pasteur of Shanghai, Chinese Acad...

11

2014-08

Researchers at Institut Pasteur of Shanghai discover a novel mechanism that promotes human Treg stability under inflammation

On August 5, the international academic journal Journal of Biological Chemistry published a research article entitled“PIM1 Kinase Phosphorylates the Human Transcription Factor FOXP3 at Serine 422 to Negatively Regulate its Activity under Inflammation” from the Unit of Molecular Immunology, Inst...On August 5, the international academic journal Journal of Biological Chemistry published a research article entitled“PIM1 Kinase Phosphorylates the Human Transcription Factor FOXP3 at Serine 422 to Negatively Regulate its Activity under Inflammation” from the Unit of Molecular Immunology, Inst...

28

2014-07

Researchers at Institut Pasteur of Shanghai discover a novel mechanism that regulates influenza A virus survival

On July 24, Journal of Virology published a research article entitled “Sumoylation of Influenza A Virus Nucleoprotein Is Essential for Intracellular Trafficking and Virus Growth” from the unit of molecular virology, Institut Pasteur of Shanghai, Chinese Academy of Sciences. This article reveals...On July 24, Journal of Virology published a research article entitled “Sumoylation of Influenza A Virus Nucleoprotein Is Essential for Intracellular Trafficking and Virus Growth” from the unit of molecular virology, Institut Pasteur of Shanghai, Chinese Academy of Sciences. This article reveals...