Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

29

2015-10

Researchers at Institut Pasteur of Shanghai report that Vaccination with heterologous HIV envelope sequences and heterologous adenovirus vectors increases T cell responses to conserved regions

On October 15th, the international clinical research journal Journal of Infectious Diseases (JID) published the Phase I clinical trial of candidate HIV vaccines entitled " Vaccination with heterologous HIV envelope sequences and heterologous adenovirus vectors increases T cell responses to conser...On October 15th, the international clinical research journal Journal of Infectious Diseases (JID) published the Phase I clinical trial of candidate HIV vaccines entitled " Vaccination with heterologous HIV envelope sequences and heterologous adenovirus vectors increases T cell responses to conser...

22

2015-10

Researchers at Institut Pasteur of Shanghai identify a novel molecular pathway for the Th17 cells

The Journal of Biological Chemistry (JBC) published online the research conductedby Li Bin from Institut Pasteur of Shanghai, CAS and Lv Lin from rheumatism department of Fudan university Huashan hospital: TRAF5 Mediated K63-linked Polyubiquitination Plays an Essential Role in the Positive regul...The Journal of Biological Chemistry (JBC) published online the research conductedby Li Bin from Institut Pasteur of Shanghai, CAS and Lv Lin from rheumatism department of Fudan university Huashan hospital: TRAF5 Mediated K63-linked Polyubiquitination Plays an Essential Role in the Positive regul...

12

2015-10

Researchers at Institut Pasteur of Shanghai identify a novel molecular pathway for the regulatory of Treg cells

On October 1, Journal of Biological Chemistry published a research work online entitled “Poly(ADP-ribosyl)ation of FOXP3 Mediated by PARP-1 Regulates the Function of Regulatory T Cells” from a team of researchers led by Bin Li, Institut Pasteur of Shanghai, Chinese Academy of Sciences. This stu...On October 1, Journal of Biological Chemistry published a research work online entitled “Poly(ADP-ribosyl)ation of FOXP3 Mediated by PARP-1 Regulates the Function of Regulatory T Cells” from a team of researchers led by Bin Li, Institut Pasteur of Shanghai, Chinese Academy of Sciences. This stu...

12

2015-10

Researchers at Institut Pasteur of Shanghai identify a miRNA that promotes human Treg cell stability under inflammation

FOXP3+ Treg cells play a central role in maintaining the balance between immune tolerance and activation. Treg cells have a great plasticity and are not stable under inflammation and other physiological conditions. For instance, upon IL-6 stimulationTreg cells can lose the expression of FOXP3 and...FOXP3+ Treg cells play a central role in maintaining the balance between immune tolerance and activation. Treg cells have a great plasticity and are not stable under inflammation and other physiological conditions. For instance, upon IL-6 stimulationTreg cells can lose the expression of FOXP3 and...