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2012-01Thus developing reliable culture conditions for the large scale human monoclonal antibody production are practically important. Since it was introduced in late 1990s Wave bioreactor has been used for protein production by mammalian and insect cells. These results strongly support for using Wave b...On December 25, 2011, Molecular Biotechnology published online a research article entitled “High Yield of Human Monoclonal Antibody Produced by Stably Transfected Drosophila Schneider 2 Cells in Perfusion Culture Using Wave Bioreactor” by Paul Zhou’s laboratory at the Institut Pasteur of shang...
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2011-12Penicillium marneffei (P. marneffei) is considered an indicator pathogen of AIDS, and the endemicity and clinical features of P. marneffei have been described. While, how the co-infection of P. marneffei exacerbate deterioration of the immune response remains poorly understood.
Professor WANG...
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2011-12Prof. SUN Bing with his team at Shanghai Institute of Pasteur, CAS, found that PB1 of avian influenza A virus contributes to higher polymerase activity than PB1 from human influenza A virus, and 473V and 598P are responsible for this role. This founding indicates a new mechanism for adaptation of...
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2011-11Only a limited number of JEV-infected individuals show symptoms and induce severe encephalitis,that indicating host-dependent susceptibilities. The reason that people have different susceptibilities to JEV remains unclear. Clinical manifestations of JEV infections in laboratory mice closely resem...Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus. The infectious disease it causes is encephalitis. China is one of the countries with high incidence of encephalitis. Only a limited number of JEV-infected individuals show symptoms and induce severe encephalitis, that indicating h...