Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

13

2013-06

Scientists Determine Unusual Architecture of the p7 Channel from Hepatitis C Virus

Hepatitis C virus (HCV) is one of the major pathogens which will cause chronic hepatitis, cirrhosis, and hepatocelluar carcinoma. A protective vaccine is not yet available and the standard treatment with PEG-interferon alpha plus ribavirin usually takes more than one year and has strong side effe...Hepatitis C virus (HCV) is one of the major pathogens which will cause chronic hepatitis, cirrhosis, and hepatocelluar carcinoma. A protective vaccine is not yet available and the standard treatment with PEG-interferon alpha plus ribavirin usually takes more than one year and has strong side effe...

06

2013-06

Chinese Scientists Discover Drug Resistant Mutations in Severe Cases of H7N9 Infected Individuals

Recently, Chinese scientists published their research results on the Lancet. The study shows that H7N9 infected patients with severe outcomes have been identified antiviral resistance mutations. The project was initiated by the Shanghai Public Health Clinical Centre (SPHCC), China. Dr. HAO Pei fr...

08

2013-05

IPS Researchers find novel molecular mechanism of MLL5 protein in cell cycle regulation

Mixed Lineage Leukemia 5 (MLL5) protein is a major member of histone H3K4 methyltransfereases, Its coding gene Mll5was located within chromosome band 7q22, which is frequently deleted in human acute myeloid leukemia. The previous study of Mll5 gene knockout mouse indicated that Mll5 gene is an im...Mixed Lineage Leukemia 5 (MLL5) protein is a major member of histone H3K4 methyltransfereases, Its coding gene Mll5was located within chromosome band 7q22, which is frequently deleted in human acute myeloid leukemia. The previous study of Mll5 gene knockout mouse indicated that Mll5 gene is an im...

28

2013-04

IPS researchers identified a new molecular pathway to control inflammation

On April 22, a study from the Key Laboratory of Molecular Virology and Immunology at the Institut Pasteur of Shanghai, Chinese Academy of Sciences（IPS-CAS） was released in the Journal of Biological Chemistry, entitled “TIP60 Positively regulates ThPOK-Mediated Repression of Eomesodermin in Hum...On April 22, a study from the Key Laboratory of Molecular Virology and Immunology at the Institut Pasteur of Shanghai, Chinese Academy of Sciences（IPS-CAS） was released in the Journal of Biological Chemistry, entitled “TIP60 Positively regulates ThPOK-Mediated Repression of Eomesodermin in Hum...