Research Progress--Shanghai Institut of Immunity and Infection, Chinese Academy of Sciences

23

2013-08

IPS Researchers discover new molecular pathway to fight inflammation

Regulator T (nTreg) cells are suppressive cells that control excessive inflammation and mediate immune tolerance. Foxp3 is a crucial transcription factor for Treg differentiation and function. Since inflammation is a regular event in immune effector responses, it may be necessary to disrupt Treg ...Regulatory T (nTreg) cells are suppressive cells that control excessive inflammation and mediate immune tolerance. Foxp3 is a crucial transcription factor for Treg differentiation and function. Since inflammation is a regular event in immune effector responses, it may be necessary to disrupt Treg...

07

2013-08

Virology: protecting flu patients from themselves

Drugs that suppress the inflammatory response could reduce mortality risk for influenza patients when combined with standard antiviral care, new research shows. Several studies have suggested that a strong inflammatory response to infection with influenza may be linked to increased disease severi...

09

2013-07

IPS researchers discover an immune evasion mechanism in the severe malaria parasite

Dr. JIANG Lubin’s group in the Institut Pasteur of Shanghai, Chinese Academy of Sciences (IPS-CAS) has recently discovered an immune evasion mechanism in the severe malaria parasite, which may also be applied to the development of a malaria vaccine. “The implications of these results for our un...Dr. JIANG Lubin’s group in the Institut Pasteur of Shanghai, Chinese Academy of Sciences (IPS-CAS) has recently discovered an immune evasion mechanism in the severe malaria parasite, which may also be applied to the development of a malaria vaccine. “The implications of these results for our un...

13

2013-06

Scientists Determine Unusual Architecture of the p7 Channel from Hepatitis C Virus

Hepatitis C virus (HCV) is one of the major pathogens which will cause chronic hepatitis, cirrhosis, and hepatocelluar carcinoma. A protective vaccine is not yet available and the standard treatment with PEG-interferon alpha plus ribavirin usually takes more than one year and has strong side effe...Hepatitis C virus (HCV) is one of the major pathogens which will cause chronic hepatitis, cirrhosis, and hepatocelluar carcinoma. A protective vaccine is not yet available and the standard treatment with PEG-interferon alpha plus ribavirin usually takes more than one year and has strong side effe...